Traditional gene carriers are cationic to
allow efficient loading with anionic genes but these carriers are toxic
limiting clinical applications. Now
researchers report neutral liposomes containing DNA and PCR components which
amplify the DNA. Transfection rates are
similar to the traditional cationic vectors, but cell viability significantly
improved.
http://pubs.acs.org/doi/pdfplus/10.1021/nn501106a
DNA amplification in
neutral liposomes for safe and efficient gene delivery; S. Lee et al; ACS Nano
Just Accepted Manuscript; DOI: 10.1021/nn501106a
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