Tuesday, 6 May 2014

Bone marrow on a chip

Bone marrow grown within a device implanted in a mouse resembles natural marrow, researchers reported.  The tissue could be explanted whole, inserted into a lab-on-a-chip and maintained in vitro for 7 days.  The cultured marrow mimicked tissue responses to radiation toxicity and treatment for exposure normally only observed in vivo.

Bone marrow-on-a-chip replicates hematopoietic niche physiology in vitro; Y-S Torisawa et al; Nature Methods AOP doi:10.1038/nmeth.2938

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