Researchers have combined sol-gel processing with electrospinning
to produce cotton-wool-like CaO-SiO2 glass structures. The cotton-wool-like morphology was
attributed to the rheological properties of the electrospinning solution causing
branching of the primary jet and to fibre regions rich in calcium ions creating
bending instabilites in the applied electric field. The material was moldable and could be packed
into complex bone defects. Preliminary
results suggested the materials were bioactive and non-cytotoxic.
Cotton-wool-like bioactive glasses for bone regeneration; G. Poologasundarampillai
et al; Acta Biomaterialia; http://dx.doi.org/10.1016/jactbio.2014.05.020
An open access paper
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