Micro-RNA-21
is overexpressed in many cancers. A new
magnetobiosensor selectively detected micro-RNA-21 at low concentrations in
cancer cells and tissue samples. RNA plant-virus proteins tethered to magnetic
beads captured DNA duplexes formed by adding anti-Micro-RNA-21 to the Micro-RNA-21-containing
samples. Beads were captured on screen-printed
electrodes for electrochemical detection of microRNA.
Magnetobiosensors
based on viral protein p19 for micro-RNA
determination in cancer cells and tissues; S. Campuzano et
al; Angewandte Chemie International Edition, DOI: 10.1002/anie.201403270
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